Role of Immunomodulatory Drugs and Proteasome Inhibitors in the Treatment of Myeloma Bone Disease: Literature of Review

International Journal of Medical Science
© 2016 by SSRG - IJMS Journal
Volume 3 Issue 7
Year of Publication : 2016
Authors : Dr. Lohit kumar Kalita, Dr. Mridul Sarma and Dr. Umesh Ch. Sarma
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Dr. Lohit kumar Kalita, Dr. Mridul Sarma and Dr. Umesh Ch. Sarma, "Role of Immunomodulatory Drugs and Proteasome Inhibitors in the Treatment of Myeloma Bone Disease: Literature of Review," SSRG International Journal of Medical Science, vol. 3,  no. 7, pp. 1-6, 2016. Crossref, https://doi.org/10.14445/23939117/IJMS-V3I7P101

Abstract:

 Multiple myeloma (MM) is a clonal plasma cell malignancy, characterized by the proliferation of neoplastic plasma · cells. Currently, with an improved understanding of the genetic as well as biological abnormalities that are a hallmark of multiple myeloma, cytogenetics, and other risk stratification methods are increasingly being proposed to guide the treatment of myeloma. Among others, recent advances have been useful in defining high-risk groups with poor outcome after standard and high-dose chemotherapies. The use of novel agents have improved prognosis for a subset of patients with high-risk disease.

Keywords:

Myeloma, Agents, Immunomodulatory.

References:

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