Drug Induced Orthodontic Tooth Movement: A Comprehensive Review

International Journal of Medical Science
© 2019 by SSRG - IJMS Journal
Volume 6 Issue 11
Year of Publication : 2019
Authors : Dr. Sagar S Bhat, Dr.Yesh Sharma,Dr. Anmol Bagaria, Dr.Shalini Sharma, Dr. Jasmine Marwaha, Ishika Verma
How to Cite?

Dr. Sagar S Bhat, Dr.Yesh Sharma,Dr. Anmol Bagaria, Dr.Shalini Sharma, Dr. Jasmine Marwaha, Ishika Verma, "Drug Induced Orthodontic Tooth Movement: A Comprehensive Review," SSRG International Journal of Medical Science, vol. 6,  no. 11, pp. 11-14, 2019. Crossref, https://doi.org/10.14445/23939117/IJMS-V6I11P104


Remodeling of the paradental tissues facilitates orthodontic tooth movement in response tomechanical forces. During orthodontic treatment, the application of sustained force on teeth which guides to tooth mobility processes that ultimately lead to alveolar bone remodeling. The present review highlights the significance for orthodontists to get a full list of all the medications being taken by every patient scheduled to undergo orthodontic treatment


Movement, Orthodontic, Tooth


[1] Sidhu S. Drug Induced Orthodontic Tooth Movement. J Adv Med Dent Scie Res 2019;7(4): 5-7
[2] Ong CK, Walsh LJ, Harbrow D, Taverne AA, Symons AL. Orthodontic tooth movement in the prednisolone-treated rat. Angle Orthod. 2000;70(2):118-25.
[3] Pithon MM, Ruellas ACO. Avaliaçãoclínica e radiográfica da influência do fenobarbital (Gardenal®) namovimentaçãoortodôntica: estudoemcoelhos. Rev Dental Press OrtodOrtop. 2008;13(1):34-42.
[4] Arantes GM, Arantes VM, Ashmawi HA, Posso IP. Tenoxicam controls pain without altering orthodontic movement of maxillary canines. OrthodCraniofac Res 2009; 12(1): 14-9.
[5] Al-Hasani N, Glares G, Albustani A, Hussain S. Clinical efficacy of locally injected calcitriol in orthodontic tooth movement. Int J Pharm PharmSci 2011; 3(5): 139-43.
[6] Pharoah MJ, Heersche JN. Dexamethasone inhibits formation of osteoclast-like cells in bone-marrow cultures. J Dent Res. 1986;65(7):1006-9.
[7] Christiansen, R. L. & Burstone, C. J. Centers of rotation within the periodontal space. Am J Orthod, 1969;55, 353-69.
[8] Masella RS, Meister M. Current concepts in the biology of orthodontic tooth movement. Am J OrthodDentofacial Orthop.2006;129:458-68.
[9] Ramos LVT, Zurquim LZ, Consolaro A. A influência de medicamentosnamovimentaçãoortodôntica: umaanálisecrítica da literatura. Rev Dental Press OrtodOrtop Facial.2005;10(1):122-30.
[10] Reinholt FP, Widholm SM, Ek-Rylander B, Andersson G. Ultrastructural localization of a tartrate-resistant acid ATPase in bone. J Bone Miner Res. 1990;5(10):1055-61.
[11] Swanson C, Lorentzon M, Conaway HH, Lerner UH. Glucocorticoid regulation of osteoclast differentiation and expression of receptor activator of nuclear factor-kappaB (NF-kappaB) ligand, osteoprotegerin, and receptor activator of NF-kappaB in mouse calvarial bones. Endocrinology. 2006;147(7):3613-22.
[12] Yamane A, Fukui T, Chiba M. In vitro measurement of orthodontic tooth movement in rats given betaaminopropionitrile or hydrocortisone using a time-lapse videotape recorder. Eur J Orthod. 1997;19(1):21-8.
[13] Patil AK, Keluskar KM and Gaitonde ST. Clinical application of prostaglandin E1 on orthodontic tooth movement – A clinical trial. J IndOrthodSoc 2005; 38:91-8.
[14] Collins MK and Sinclair PM. The local use of vitamin D to increase the rate of orthodontic tooth movement. Am J Orthod 1988; 94:278-84.
[15] Takano-Yamamoto T, Kawakami M, Kobayashi Y, Yama shiro T and Sakuda M. The Effect of local application of 1,25- dihydroxycholecalciferol on osteoclast numbers in orthodontically treated rats. J. Dent. Res 1992; 71:53-9.
[16] Kale S, Kocadereli l, Atilla P and Asan E. Comparison of the effects of 1,25 dihydroxycholecalciferol and prostaglandin E2 on orthodontic tooth movement. Am J OrthodDentofacialOrthop 2004; 125:607-14.
[17] Shirazi M, Dehpour AR, Jafari F. The effect of thyroid hormone on orthodontic tooth movement in rats. J ClinPediatr Dent. 1999;23:259–64.
[18] Madan MS, Liu ZJ, Gu GM, King GJ. Effects of human relaxin on orthodontic tooth movement and periodontalligaments in rats. 2007;131:8. Am J Orthod. 2007;131:8.e1–8.10.
[19] Dolce C, Vakani A, Archer L, Morris-Wiman JA, Holliday LS. Effects of echistatin and an RGD peptide on orthodontic tooth movement. J Dent Res. 2003;82:682–6.
[20] Krishnan V, Davidovitch Z. The effect of drugs on orthodontic tooth movement. OrthodCraniofac Res. 2006;9:163–71.
[21] Shdayfat NB. Effects of drugs on periodontal tissue remodeling and clinical responses to orthodontic mechanotherapy. Pak Oral and Dental J. 2011;31:379–88