Antibiogram of Klebsiella pneumoniae isolated from urine samples in a tertiary care hospital of Western Punjab

International Journal of Medical Science

© 2020 by SSRG - IJMS Journal

Volume 7 Issue 9

Year of Publication : 2020

Authors : Amandeep Kaur Saini, Amandeep Kaur

10.14445/23939117/IJMS-V7I9P102

How to Cite?

Amandeep Kaur Saini, Amandeep Kaur, "Antibiogram of Klebsiella pneumoniae isolated from urine samples in a tertiary care hospital of Western Punjab," SSRG International Journal of Medical Science, vol. 7,  no. 9, pp. 7-11, 2020. Crossref, https://doi.org/10.14445/23939117/IJMS-V7I9P102

Abstract:

Aim: The present study was undertaken to determine the antibiotic susceptibility pattern of Klebsiella pneumoniae causing UTI in outdoor and indoor
patients in a tertiary care hospital. Material and Methods: The samples were processed as per standard microbiological techniques. All isolates showing lactose fermenting, mucoid colonies on MacConkey agar and greyish, mucoid colonies on blood agar, gram negative coccobacilli on Gram staining were provisionally diagnosed as K. pneumoniae. The isolates were further subjected to various biochemical reactions for confirmation of K. pneumoniae. The antibiotic sensitivity testing was performed using the Kirby-Bauer disc diffusion method.
Results: A total of 1854 urine samples were processed which yielded 92 K. pneumoniae isolates. Isolates were highly sensitive to colistin and moderately sensitive to imipenem, meropenem, cefepime, gentamicin and amikacin. High level of resistance was shown for piperacillin+tazobactum, cefixime, cotrimoxazole and ciprofloxacin. Very less sensitivity was recorded for norfloxacin and nitrofurantoin which are otherwise considered as key drugs for empirical treatment of UTI.
Conclusion: This study highlights high level of resistance among K. pneumoniae isolates causing UTI. Therefore, the clinicians are left with very few options in the selection of optimal antimicrobials for empirical treatment of UTI.

Keywords:

Klebsiella pneumoniae, Urinary Tract Infections (UTI), Antibiotic susceptibility pattern.

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