Comparison of Coronary Diseases by Coronary Angiography between Diabetic and Non-Diabetic Patients

International Journal of Medical Science
© 2023 by SSRG - IJMS Journal
Volume 10 Issue 2
Year of Publication : 2023
Authors : Aymen Shaher, Bassem Marof, Arige Boubou
pdf
How to Cite?

Aymen Shaher, Bassem Marof, Arige Boubou, "Comparison of Coronary Diseases by Coronary Angiography between Diabetic and Non-Diabetic Patients," SSRG International Journal of Medical Science, vol. 10,  no. 2, pp. 1-6, 2023. Crossref, https://doi.org/10.14445/23939117/IJMS-V10I2P101

Abstract:

Cardiac adversity is by far the commonest cause of mortality in patients with diabetes.to study angiographic extents, number of coronary vessels, and type of lesions(A, B, C)and comparison the findings between diabetic and nondiabetic patients. The study included all Syrian patients who underwent a cardiac catheterization from 8 March to 8 September 2022 at Tishreen University Hospital in Latakia. It included 455 patients; 181 of them were excluded(either normal coronary arteries or the fact that the patient had previously performed a Coronary Artery Bypass Graft). Results of this comparative study: Diabetic patients had more affected arteries(3arteries:39.6% in diabetic patients and 6.7%in nondiabetic patients, two arteries:35.3% in diabetic patients and 11.9% in non-diabetic patients, 4 arteries(including left main):5.8 % diabetic patients and 1.5% non-diabetic patients, single artery:16.5%in diabetic patients and 76.3% in nondiabetic patients. The anterior descending artery is the most affected artery, with 87.8% of the left circumflex artery and 69.8% of diabetic patients. Type of lesion: Type A:7.9%in diabetic and 47.4% in non-diabetic patients, type B:57.6%in diabetic and 38.5 %in non-diabetic patients.Type C:33.8%in diabetic and 10.4%in non-diabetic patients.

Keywords:

Diabetic, Coronary Angiography, Type of lesion(A, B, C).

References:

[1] B.B. Thripaty, Complications of Diabetes :API Text Book of Medicine, 6th Edition, Association of Physicians of India, 2001.
[Google Scholar]
[2] Maerrano Rlos et al., Cardiac Complications in Diabetes: World Book of Diabetes in Practice, vol. 2, p. 169
[3] D.M. Nathan, J. Meigs, and D.E. Singer, “The Epidemiology of Cardiovascular Disease in type-2 Diabetes Mellitus: How Sweat it is…. Or is it?,” The Lancet, 1997.
[CrossRef] [Google Scholar] [Publisher link]
[4] D. Aronson, E.J. Rayfield, and J.H. Chesebro, “Mechanisms Determining Course and Outcome of Diabetic Patients who have had Acute Myocardial Infarction,” Annals of Internal Medicine, vol. 126, no. 4, pp. 296–306, 1997.
[CrossRef] [Google Scholar] [Publisher link]
[5] Sean M. Donahoe et al., “Diabetes and Mortality Following Acute Coronary Syndromes,” JAMA, vol. 298, no. 7, pp. 765–775, 2007.
[CrossRef] [Google Scholar] [Publisher link]
[6] Lucy A. Suzuki et al., “Diabetes Accelerates Smooth Muscle Accumulation in Lesions of Atherosclerosis: Lack of Direct Growth-promoting Effects of High glucose Levels Diabetes,” Diabetes, vol. 50, no. 4, pp. 851-860, 2001.
[CrossRef] [Google Scholar] [Publisher link]
[7] S.B. Williams et al., “Impaired Nitric Oxide-mediated Vasodilation in Patients with Non-insulin-dependent Diabetes Mellitus,” Journal of the American College of Cardiology, vol. 27, no. 3, pp. 567-574, 1996.
[CrossRef] [Google Scholar] [Publisher link]
[8] A.I. Vinik et al., “Platelet Dysfunction in type 2 Diabetes,” Diabetes Care, vol. 24, no. 8, pp. 1476-1485, 2001.
[CrossRef] [Google Scholar] [Publisher link]
[9] P.R. Moreno et al., “Coronary Composition and Macrophage Infiltration in Atherectomy Specimens from Patients with Diabetes Mellitus,” Circulation, vol. 102, no 18, pp. 2180-2184, 2000.
[CrossRef] [Google Scholar] [Publisher link]
[10] Raffaele Marfella et al., “The Ubiquitin-proteasome System and Inflammatory Activity in Diabetic Atherosclerotic Plaques: Effects of Rosiglitazone Treatment,” Diabetes, vol. 55, no. 3, pp. 622-632, 2006.
[CrossRef] [Google Scholar] [Publisher link]
[11] Won Sang Yoo et al., “Early Detection of Asymptomatic Coronary Artery Disease in Patients with type 2 Diabetes Mellitus,” The Korean Journal of Internal Medicine, vol. 24, no. 3, pp. 183-189, 2009.
[CrossRef] [Google Scholar] [Publisher link]
[12] John C. Pickup, “Inflammation and Activated Innate Immunity in the Pathogenesis of type 2 Diabetes,” Diabetes Care, vol. 27, no. 3, pp. 813-823, 2004.
[CrossRef] [Google Scholar] [Publisher link]
[13] Esin Eren, Necat Yilmaz, and Ozgur Aydin, “Functionally Defective High-density Lipoprotein and Paraoxonase: A Couple for Endothelial Dysfunction in Atherosclerosis,” Cholesterol, 2013.
[Google Scholar] [Publisher link]
[14] Yan Yan et al., “Identification of Plasma Vascular Endothelia-cadherin as a Biomarker for Coronary Artery Disease in Type 2 Diabetes Mellitus Patients,” International Journal of Clinical and Experimental Medicine, vol. 8, no. 10, pp. 19466-19470, 2015.
[Google Scholar] [Publisher link]
[15] Markku Laakso, “Cardiovascular Disease in type 2 Diabetes from Population to Man to Mechanisms: The Kelly West Award Lecture 2008,” Diabetes Care, vol. 33, no. 2, pp. 442-449, 2010.
[CrossRef] [Google Scholar] [Publisher link]
[16] Ravneet Kaur, “Concept of Pippali (Piper Longum) Verses Heart Diseases,” SSRG International Journal of Medical Science, vol. 6, no. 5, pp. 5-6, 2019.
[CrossRef] [Publisher link]
[17] Beatriz García-Fontana et al., “Metabolomic Profile Related to Cardiovascular Disease in Patients with type 2 Diabetes Mellitus: A Pilot Study,” Talanta, vol. 148, pp. 135-143, 2016.
[CrossRef] [Google Scholar] [Publisher link]
[18] Zheng Wang et al., “Association of Serum SPARC Level with Severity of Coronary Artery Lesion in type 2 Diabetic Patients with Coronary Heart Disease,” International Journal of Clinical and Experimental Medicine, vol. 8, no. 10, pp. 19290-19296, 2015.
[Google Scholar] [Publisher link]
[19] Sabitha Palazhy, Prakash Kamath, and Damodaran M. Vasudevan, “Elevated Oxidative Stress Among Coronary Artery Disease Patients on Statin Therapy: A Cross Sectional Study,” Indian Heart Journal, vol. 67, no. 3, pp. 227-232, 2015.
[CrossRef] [Google Scholar] [Publisher link]
[20] T. Nishikawa, D. Edelstein, and M. Brownlee, “The Missing Link: A Single Unifying Mechanism for Diabetic Complications,” Kidney International Supplement, 2000.
[CrossRef] [Google Scholar] [Publisher link]
[21] Cas Weykamp, “HbA1c: A Review of Analytical and Clinical Aspects,” Annals of Laboratory Medicine, vol. 33, no. 6, pp. 393– 400, 2013.
[CrossRef] [Google Scholar] [Publisher link]
[22] John M. Lachin, and Trevor J. Orchard, and David M. Nathan, “Update on Cardiovascular Outcomes at 30 Years of the Diabetes Control and Complications Trial/Epidemiology of Diabetes Interventions and Complications Study,” Diabetes Care, vol. 37, no. 1, pp. 39–43, 2014.
[CrossRef] [Google Scholar] [Publisher link]
[23] J. Kuusisto et al., “NIDDM and Its Metabolic Control Predict Heart Disease in Elderly Subjects,” Diabetes, vol. 43, no. 8, pp. 960– 967, 1994.
[CrossRef] [Google Scholar] [Publisher link]
[24] Mahdi Mossavi, Ebrahim Nematipour, and Maryam Mehrpooya, “Comparison of Extent of Coronary Artery Disease in Angiography of Diabetics and Non-diabetics,” Iranian Heart Journal, vol. 7, no. 4, pp. 37-42, 2006.
[Google Scholar] [Publisher link]
[25] S.N. Uddin et al., “Angiographic Severity and Extent of Coronary Artery Disease in Patients with type 2 Diabetes Mellitus,” Mymensingh Medical Journal, vol. 14, no. 1, pp. 32-37, 2005.
[Google Scholar] [Publisher link]
[26] Stephen J. Nichoils et al., “Effect of Diabetes on Progression of Coronary Atherosclerosis and Arterial Remodeling: A Pooled Analysis of Intravascular Ultrasound Trials,” Journal of the American College of Cardiology, vol. 52, no. 4, pp. 255-262, 2008.
[CrossRef] [Google Scholar] [Publisher link]
[27] Jamal S. Rana et al., “Difference in Prevalence, Extent, Severity and Prognosis of Coronary Artery Disease among Patients with and Without Diabetes Undergoing Coronary Computed Tomography Angiography,” Diabetes Care, vol. 35, no. 8, pp. 1787-1794, 2012.
[CrossRef] [Google Scholar] [Publisher link]
[28] Srinidhi S. Hegde et al., “Comparitive Angiographic Profile in Diabetic and Non-diabetic Patients with Acute Coronary Syndrome,” Journal of Clinical and Diagnostic Research, vol. 8, no. 9, 2014.
[CrossRef] [Google Scholar] [Publisher link]
[29] Thomas W. Jax et al., “Hemostatic Risk Factors in Patients with Coronary Artery Disease and type 2 Diabetes – A Two Year Follow-up of 243 Patients,” Cardiovasc Diabetol, 2009.
[CrossRef] [Google Scholar] [Publisher link]