Designing, Simulation, and Performance-based Screening for a Power-Efficient Operational Transconductance Amplifier (OTA) Utilizing CNTFET Technology at a 22nm Node for Biomedical Applications

International Journal of Electrical and Electronics Engineering

© 2025 by SSRG - IJEEE Journal

Volume 12 Issue 2

Year of Publication : 2025

Authors : S. Bashiruddin, P. Gupta, M. Nizamuddin

10.14445/23488379/IJEEE-V12I2P112

How to Cite?

S. Bashiruddin, P. Gupta, M. Nizamuddin, "Designing, Simulation, and Performance-based Screening for a Power-Efficient Operational Transconductance Amplifier (OTA) Utilizing CNTFET Technology at a 22nm Node for Biomedical Applications," SSRG International Journal of Electrical and Electronics Engineering, vol. 12,  no. 2, pp. 102-112, 2025. Crossref, https://doi.org/10.14445/23488379/IJEEE-V12I2P112

Abstract:

Extremely low-frequency variations are often associated with physiological signals. Therefore, while acquiring physiological signals of human origin, the signal acquisition system interferes with several artefacts and noises. Thus, acquiring noise-free physiological signals of human origin using miniaturized, low-power external or implantable measurement devices is paramount for diagnostic and therapeutic purposes. The OTA serves as a basic component in analog signal-processing circuits, making it ideal for low-frequency electronic signal processing. Pure CNTFET, CNTFET-MOSFET hybridized, and MOSFET-based OTA-C circuits suitable for processing biomedical signals were designed at a 22 nm technology node and simulated to assess their performance using HSPICE. The design parameters included a Carbon Nanotube (CNT) diameter of 1.5 nm (with a chirality of (19, 0), a total of 10 CNTs/CNTFETs, and a pitch of 20 nm. The circuit was designed using a channel length of 22 nm and a channel width of MOSFET 381.5 nm. Following a curious analysis of the performance parameters, pure CNTFET-based OTA-C was screened as the most appropriate model for biomedical applications among all the four proposed OTA-C models as it exhibited high gain (38 dB), high phase margin (90.7◦), high unit gain frequency (19 MHz), and low power consumption (29 μW). The proposed pure CNTFET-based OTA-C was a high-gain-low-power-consuming stable building block (amplifier) appropriate for generating various diagnostic and therapeutic biomedical devices.

Keywords:

HSPICE, CNTFET, OTA, Biomedical, Nano-electronics, DC gain, Bandwidth.

References:

[1] Shahram H. Hesari et al., “Ultra Low-Power OTA for Biomedical Applications,” United States National Committee of URSI National Radio Science Meeting, Boulder, CO, USA, pp. 1-2, 2019.
[CrossRef] [Google Scholar] [Publisher Link]
[2] M.A. Tooley, “Electronics and Biological Signal Processing,” BJA Education, vol. 23, no. 4, pp. 122-127, 2023.
[CrossRef] [Google Scholar] [Publisher Link]
[3] Israa Y.I. AbuShawish et al., “Biomedical Amplifiers Design Based on Pseudo-Resistors: A Review,” IEEE Sensors Journal, vol. 23, no. 14, pp. 15225-15238, 2023.
[CrossRef] [Google Scholar] [Publisher Link]
[4] Noura AlHinai, Chapter 1 - Introduction to Biomedical Signal Processing and Artificial Intelligence, Biomedical Signal Processing and Artificial Intelligence in Healthcare, pp. 1-28, 2020.
[CrossRef] [Google Scholar] [Publisher Link]
[5] Hui Zhang, Yajie Qin, and Zhiliang Hong, “A 1.8-V 770-Nw Biopotential Acquistion System for Portable Applications,” IEEE Biomedical Circuits and Systems Conference, Beijing, China, pp. 93-96, 2009.
[CrossRef] [Google Scholar] [Publisher Link]
[6] Xiao Zhao et al., “Low-Voltage Process-Insensitive Frequency Compensation Method for Two-Stage OTA with Enhanced DC Gain,” AEU-International Journal of Electronics and Communications, vol. 69, no. 3, pp. 685-690, 2015.
[CrossRef] [Google Scholar] [Publisher Link]
[7] Mohamed B. Elamien, and Soliman A. Mahmoud, “Analysis and Design of a Highly Linear CMOS OTA for Portable Biomedical Applications in 90 nm CMOS,” Microelectronics Journal, vol. 70, pp. 72-80, 2017.
[CrossRef] [Google Scholar] [Publisher Link]
[8] Wazir Singh et al., “Energy Efficient Biopotential Acquisition Unit for Wearable Health Monitoring Applications,” 18th International Symposium on Quality Electronic Design, Santa Clara, CA, USA, pp. 337-341, 2017.
[CrossRef] [Google Scholar] [Publisher Link]
[9] Montree Kumngern et al., “Nanopower Multiple-Input Dtmos OTA and its Applications to High-Order Filters for Biomedical Systems,” AEU - International Journal of Electronics and Communications, vol. 130, 2021.
[CrossRef] [Google Scholar] [Publisher Link]
[10] Ricardo Póvoa et al., “A New Family of CMOS Inverter-Based OTAs for Biomedical and Healthcare Applications,” Integration, vol. 71, pp. 38-48, 2020.
[CrossRef] [Google Scholar] [Publisher Link]
[11] B.N. Ray, P.P. Chaudhuri, and P.K. Nandi, “Efficient Synthesis of OTA Network For Linear Analog Functions,” IEEE Transactions on Computer-Aided Design of Integrated Circuits and Systems, vol. 21, no. 5, pp. 517-533, 2002.
[CrossRef] [Google Scholar] [Publisher Link]
[12] R. Harjani, R. Heineke, and Feng Wang, “An Integrated Low-Voltage Class AB CMOS OTA,” IEEE Journal of Solid-State Circuits, vol. 34, no. 2, pp. 134-142, 1999.
[CrossRef] [Google Scholar] [Publisher Link]
[13] Rajeshwari S. Mathad et al., “Design of OTA-C Notch Filter in Mega Hertz Frequency Range,” International Journal of Engineering Research and Development, vol. 10, no. 3, pp. 48-54, 2014.
[Google Scholar] [Publisher Link]
[14] Mohd Yasir, and Naushad Alam, “Systematic Design of Cntfet Based OTA and OP Amp Using gm/ID Technique,” Analog Integrated Circuits and Signal Processing, vol. 102, no. 2, pp. 293-307, 2020.
[CrossRef] [Google Scholar] [Publisher Link]
[15] Krishna C. Saraswat et al., “Performance Limitations of Si CMOS and Alternatives for Nanoelectronics,” International Journal of High Speed Electronics and Systems, vol. 16, no. 1, pp. 175-192, 2006.
[CrossRef] [Google Scholar] [Publisher Link]
[16] N. Raj et al., “A Low Power OTA for Biomedical Applications,” Cyber Journals: Multidisciplinary Journals in Science and Technology, Journal of Selected Areas in Bioengineering (JSAB), pp. 1-5, 2010.
[Google Scholar] [Publisher Link]
[17] Fernando Paixão Cortes, Eric Fabris, and Sergio Bampi, “Analysis and Design of Amplifiers and Comparators in CMOS 0.35 μm Technology,” Microelectronics Reliability, vol. 44, no. 4, pp. 657-664, 2004.
[CrossRef] [Google Scholar] [Publisher Link]
[18] Yi-Sheng Chen, Po-Yen Lin, and Yue-Der Lin, “A Novel PLI Suppression Method in ECG by Notch Filtering with a Modulation-Based Detection and Frequency Estimation Scheme,” Biomedical Signal Processing and Control, vol. 62, 2020.
[CrossRef] [Google Scholar] [Publisher Link]
[19] Raju Hajare et al., “Performance Enhancement of Finfet and Cntfet at Different Node Technologies,” Microsystem Technologies, vol. 22, pp. 1121-1126, 2016.
[CrossRef] [Google Scholar] [Publisher Link]
[20] G. Saiphani Kumar, Amandeep Singh, and Balwinder Raj, “Design and Analysis of A Gate-All-Around Cntfet-Based Sram Cell,” Journal of Computational Electronics, vol. 17, pp. 138-145, 2018.
[CrossRef] [Google Scholar] [Publisher Link]
[21] Amandeep Singh, Mamta Khosla, and Balwinder Raj, “Analysis of Electrostatic Doped Schottky Barrier Carbon Nanotube Fet for Low Power Applications,” Journal of Materials Science: Materials in Electronics, vol. 28, pp. 1762-1768, 2017.
[CrossRef] [Google Scholar] [Publisher Link]
[22] Mingcan Cen, Shuxiang Song, and Chaobo Cai, “A High Performance Cnfet-Based Operational Transconductance Amplifier and Its Applications,” Analog Integrated Circuits and Signal Processing, vol. 91, pp. 463-472, 2017.
[CrossRef] [Google Scholar] [Publisher Link]
[23] Angada B. Sachid, Min-Cheng Chen, and Chenming Hu, “FinFET with High-k Spacers for Improved Drive Current,” IEEE Electron Device Letters, vol. 37, no. 7, pp. 835-838, 2016.
[CrossRef] [Google Scholar] [Publisher Link]
[24] Trapti Sharma, and Laxmi Kumre, “Cntfet-Based Design of Ternary Arithmetic Modules,” Circuits, Systems, and Signal Processing, vol. 38, pp. 4640-4666, 2019.
[CrossRef] [Google Scholar] [Publisher Link]
[25] Mindy D. Bishop et al., “Fabrication of Carbon Nanotube Field-Effect Transistors in Commercial Silicon Manufacturing Facilities,” Nature Electronics, vol. 3, no. 8, pp. 492-501, 2020.
[CrossRef] [Google Scholar] [Publisher Link]
[26] G. Gelao, R. Marani, and A. Perri, “Study of Power Gain Capability of CNTFET Power Amplifier in THz Frequency Range,” ECS Journal of Solid State Science and Technology, vol. 11, no. 8, 2022.
[CrossRef] [Google Scholar] [Publisher Link]
[27] Yuchi Che et al., “Review of Carbon Nanotube Nanoelectronics and Macroelectronics,” Semiconductor Science and Technology, vol. 29, no. 7, 2014.
[CrossRef] [Google Scholar] [Publisher Link]
[28] Feng Yang et al., “Chirality Pure Carbon Nanotubes: Growth, Sorting, And Characterization,” Chemical Reviews, vol. 120, no. 5, pp. 2693-2758, 2020.
[CrossRef] [Google Scholar] [Publisher Link]
[29] Nigar Anzar et al., “Carbon Nanotube - A Review on Synthesis, Properties and Plethora of Applications in the Field of Biomedical Science,” Sensors International, vol. 1, 2020.
[CrossRef] [Google Scholar] [Publisher Link]
[30] Shimaa Ibrahim Sayed, Mostafa Mamdouh Abutaleb, and Zaki Bassuoni Nossair, “Optimization of Cnfet Parameters for High Performance Digital Circuits,” Advances in Materials Science and Engineering, vol. 2016, no. 1, 2016.
[CrossRef] [Google Scholar] [Publisher Link]
[31] Lian-Mao Peng, Zhiyong Zhang, and Sheng Wang, “Carbon Nanotube Electronics: Recent Advances,” Materials Today, vol. 17, no. 9, pp. 433-442, 2014.
[CrossRef] [Google Scholar] [Publisher Link]
[32] Sanjay Singh Rajput et al., “Design of Low-Power High-Gain Operational Amplifier for Bio-Medical Applications,” IEEE Computer Society Annual Symposium on VLSI, Pittsburgh, PA, USA, pp. 355-360, 2016.
[CrossRef] [Google Scholar] [Publisher Link]
[33] K. Bult, and G.J.G.M. Geelen, “A Fast-Settling CMOS OP Amp for SC Circuits with 90-Db DC Gain,” IEEE Journal of Solid-State Circuits, vol. 25, no. 6, pp. 1379-1384, 1990.
[CrossRef] [Google Scholar] [Publisher Link]
[34] R.G.H. Eschauzier, R. Hogervorst, and J.H. Huijsing, “A Programmable 1.5 V CMOS Class-AB Operational Amplifier with Hybrid Nested Miller Compensation for 120 Db Gain and 6 Mhz UGF,” IEEE Journal of Solid-State Circuits, vol. 29, no. 12, pp. 1497-1504, 1994.
[CrossRef] [Google Scholar] [Publisher Link]
[35] Shikha Soni, Vandana Niranjan, and Ashwni Kumar., “Design of High Gain and High Bandwidth Operational Transconductance Amplifier (OTA),” International Journal of Electronics, vol. 109, no. 5, pp. 774-793, 2022.
[CrossRef] [Google Scholar] [Publisher Link]
[36] Aman Kaushik, and Rajesh Mehra, “Design of Operational Amplifier in 45nm Technology,” International Journal of Engineering Trends and Technology, vol. 36, no. 3, 2016.
[CrossRef] [Google Scholar] [Publisher Link]
[37] Omar Abdelfattah et al., “A 0.35-V Bulk-Driven Self-Biased OTA With Rail-to-Rail Input Range in 65 Nm CMOS,” IEEE International Symposium on Circuits and Systems, Lisbon, Portugal, pp. 257-260, 2015.
[CrossRef] [Google Scholar] [Publisher Link]
[38] Sajad A. Loan et al., “High Performance Carbon Nanotube Based Cascode Operational Transconductance Amplifiers,” Proceedings of the World Congress on Engineering, London, U.K., vol. 1, pp. 1-5, 2014.
[Google Scholar] [Publisher Link]
[39] S. Wilfred Melvin, “Technology Effects on OTA Performance: A Comparative Study of 32nm CMOS and CNFET Technology,” 2024 International Conference on Integrated Circuits, Communication, and Computing Systems, Una, India, vol. 1, pp. 1-6, 2024.
[CrossRef] [Google Scholar] [Publisher Link]
[40] Anantha P. Chandrakasan, Naveen Verma, and Denis C. Daly, “Ultralow-Power Electronics for Biomedical Applications,” Annual Review of Biomedical Engineering, vol. 10, no. 1, pp. 247-274, 2008.
[CrossRef] [Google Scholar] [Publisher Link]
[41] Kateryna Bazaka, and Mohan V. Jacob, “Implantable Devices: Issues and Challenges,” Electronics, vol. 2, no. 1, pp. 1-34, 2012.
[CrossRef] [Google Scholar] [Publisher Link]
[42] Katrine Lundager et al., “Low Power Design for Future Wearable and Implantable Devices,” Journal of Low Power Electronics and Applications, vol. 6, no. 4, p. 20, 2016.
[CrossRef] [Google Scholar] [Publisher Link]
[43] Srinivasa R. Sridhara et al., “Microwatt Embedded Processor Platform for Medical System-on-Chip Applications,” IEEE Journal of Solid-State Circuits, vol. 46, no. 4, pp. 721-730, 2011.
[CrossRef] [Google Scholar] [Publisher Link]
[44] Seokheun Choi, “Powering Point-of-Care Diagnostic Devices,” Biotechnology Advances, vol. 34, no. 3, pp. 321-330, 2016.
[CrossRef] [Google Scholar] [Publisher Link]
[45] Vikrant Bhatnagar, and Philip Owende, “Energy Harvesting for Assistive and Mobile Applications,” Energy Science & Engineering, vol. 3, no. 3, pp. 153-173, 2015.
[CrossRef] [Google Scholar] [Publisher Link]
[46] A. Ghafari et al., “Batteries Applications In The Biomedical Industry: A Review,” Jnanoscitec, vol. 10, pp. 33-51, 2023.
[Google Scholar] [Publisher Link]
[47] Raihana Bahru, Azrul Azlan Hamzah, and Mohd Ambri Mohamed, “Thermal Management of Wearable and Implantable Electronic Healthcare Devices: Perspective and Measurement Approach,” International Journal of Energy Research, vol. 45, no. 2, pp. 1517-1534, 2021.
[CrossRef] [Google Scholar] [Publisher Link]
[48] Mahammad A. Hannan et al., “Energy Harvesting for the Implantable Biomedical Devices: Issues and Challenges,” Biomedical Engineering Online, vol. 13, pp. 1-23, 2014.
[CrossRef] [Google Scholar] [Publisher Link]
[49] H. Lampinen, and O. Vainio, “An Optimization Approach to Designing OTAs for Low-Voltage Sigma-Delta Modulators,” IEEE Transactions on Instrumentation and Measurement, vol. 50, no. 6, pp. 1665-1671, 2001.
[CrossRef] [Google Scholar] [Publisher Link]
[50] Tripurari Sharan, and Vijaya Bhadauria, “Fully Differential Operational Transconductance Amplifier with Enhanced Phase Margin and Gain for Ultra-Low-Power Circuits,” Journal of Low Power Electronics, vol. 13, no. 3, pp. 520-535, 2017.
[CrossRef] [Google Scholar] [Publisher Link]
[51] Mohammed Abdulaziz, Markus Törmänen, and Henrik Sjöland, “A Compensation Technique for Two-Stage Differential OTAS,” IEEE Transactions on Circuits and Systems II: Express Briefs, vol. 61, no. 8, pp. 594-598, 2014.
[CrossRef] [Google Scholar] [Publisher Link]
[52] Misari K. Shah, Vilas H. Gaidhane, and Chippy Prasannan, “Stability Analysis of Two-Stage OTA with Frequency Compensation,” IEEE International IOT, Electronics and Mechatronics Conference, Toronto, ON, Canada, pp. 1-6, 2021.
[CrossRef] [Google Scholar] [Publisher Link]
[53] J. Shailaja, and V.S.V. Prabhakar, “A Programmable Gain Amplifier Based on a Two-Level Cntfet OP Amp with Optimized Trans-Conductance to Drain Current Ratio,” Analog Integrated Circuits and Signal Processing, vol. 118, no. 2, pp. 355-369, 2024.
[CrossRef] [Google Scholar] [Publisher Link]
[54] Francesco Centurelli et al., “A Novel OTA Architecture Exploiting Current Gain Stages to Boost Bandwidth and Slew-Rate,” Electronics, vol. 10, no. 14, 2021.
[CrossRef] [Google Scholar] [Publisher Link]