Swin-Integrated Cell Detection Model for Embryo Imaging and Morphological Evaluation

International Journal of Electronics and Communication Engineering
© 2025 by SSRG - IJECE Journal
Volume 12 Issue 12
Year of Publication : 2025
Authors : R. Barkavi, G. Yamuna, C. Jayaram
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How to Cite?

R. Barkavi, G. Yamuna, C. Jayaram, "Swin-Integrated Cell Detection Model for Embryo Imaging and Morphological Evaluation," SSRG International Journal of Electronics and Communication Engineering, vol. 12,  no. 12, pp. 75-87, 2025. Crossref, https://doi.org/10.14445/23488549/IJECE-V12I12P107

Abstract:

Accurate analysis of embryonic cell structures is important to evaluate the embryo quality during early developmental stages. The overlapping blastomeres, fragmentation, and irregular morphologies in microscopic images complicate the cell counting and centroid localization procedure. Conventional methods that utilize convolutions and progressive upsampling struggle to model long-range dependencies and adapt to the dense cell regions’ spatial irregularities. This research work is proposed with the objective of developing a precise and adaptable model to overcome the limitations in conventional methods. The proposed SwinDePeriNet is a combination of a hierarchical Swin Transformer encoder with a deformable perceptual module, which is specifically developed to capture the dynamic spatial relationships and structural variations. Additionally, a Gaussian-based probabilistic estimator is incorporated to generate localized confidence maps for accurate centroid detection. The proposed model is trained and tested using a benchmark cell image dataset and exhibited 95.3% accuracy, 97.6% R² score, 26 MAE, 250 MSE, 93.1% perfect localization rate, 5.2 pixels mean Euclidean error, and a false positive rate of 2.6% which is better than conventional models.

Keywords:

Microscopic Embryo Imaging, Cell Count Regression, Centroid Detection, Framework, Spatial Confidence Mapping, Transformer-Based Encoding, Deformable Context Fusion, Gaussian Localization.

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